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One of the internal factors that affect the heterogeneity of tumor metabolism includes provision of oxygen and substrates through different perfusion levels, exceeding the tumor genotype

doi: 10.1021/ja01041a036

In one study, patients with BCC located in the perianal and genital areas were 73 years old on average, 36% had a history of skin cancer at sun-exposed sites, and 21% likely had a related disease